General Information of the Compound
Compound ID
CP0535326
Compound Name
2-(2-chloro-6-methoxyphenyl)-N-ethyl-4-methoxy-N-naphthalen-1-yl-5,6,7,8-tetrahydroquinolin-5-amine
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Structure
Formula
C29H29ClN2O2
Molecular Weight
473.016
Canonical SMILES
CCN(C1CCCc2nc(cc(OC)c12)-c1c(Cl)cccc1OC)c1cccc2ccccc12
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InChI
InChI=1S/C29H29ClN2O2/c1-4-32(24-15-7-11-19-10-5-6-12-20(19)24)25-16-9-14-22-29(25)27(34-3)18-23(31-22)28-21(30)13-8-17-26(28)33-2/h5-8,10-13,15,17-18,25H,4,9,14,16H2,1-3H3
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InChIKey
YHJWLTLIFNXJBY-UHFFFAOYSA-N
Physicochemical Property
logP
7.4763
Rotatable Bonds
6
Heavy Atom Count
34
Polar Areas
34.59
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 25191898
SID: 57300523
ChEMBL ID
CHEMBL411265
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02772, C5a anaphylatoxin chemotactic receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937 Homo sapiens (Human)  1
1
IC50 = 110 nM
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