General Information of the Compound
Compound ID
CP0533142
Compound Name
US8952150, 43
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Structure
Formula
C37H46N8O7
Molecular Weight
714.824
Canonical SMILES
COC(=O)CCCCCCNC(=O)c1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(O)cc3)n2)cc1
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InChI
InChI=1S/C37H46N8O7/c1-50-32(47)11-7-2-3-8-20-38-34(49)28-12-14-29(15-13-28)41-36-43-35(44-37(45-36)42-30-16-18-31(46)19-17-30)40-22-24-52-26-25-51-23-21-39-33(48)27-9-5-4-6-10-27/h4-6,9-10,12-19,46H,2-3,7-8,11,20-26H2,1H3,(H,38,49)(H,39,48)(H3,40,41,42,43,44,45)
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InChIKey
QUGOGIMKYSACGJ-UHFFFAOYSA-N
Physicochemical Property
logP
4.7928
Rotatable Bonds
23
Heavy Atom Count
52
Polar Areas
197.95
Hydrogen Bond Donor Count
6
Hydrogen Bond Acceptor Count
13
Complexity
52

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 51038466
SID: 117698955
ChEMBL ID
CHEMBL3650463
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06205, Solute carrier organic anion transporter family member 2A1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000031 MDCK Canis lupus familiaris (Dog)  1
1
IC50 = 1300 nM
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   LO
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