General Information of the Compound
Compound ID
CP0532983
Compound Name
N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-2-quinolin-6-ylacetamide
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Structure
Formula
C20H18N2O3
Molecular Weight
334.375
Canonical SMILES
O=C(Cc1ccc2ncccc2c1)NCC1COc2ccccc2O1
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InChI
InChI=1S/C20H18N2O3/c23-20(11-14-7-8-17-15(10-14)4-3-9-21-17)22-12-16-13-24-18-5-1-2-6-19(18)25-16/h1-10,16H,11-13H2,(H,22,23)
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InChIKey
CALOIORLZPQHQM-UHFFFAOYSA-N
Physicochemical Property
logP
2.7335
Rotatable Bonds
4
Heavy Atom Count
25
Polar Areas
60.45
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 166309839
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT05383, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 13480 nM
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