General Information of the Compound
Compound ID
CP0532447
Compound Name
(2R)-1-benzyl-N-[3-[4-(3-ethyl-2-oxobenzimidazol-1-yl)piperidin-1-yl]propyl]pyrrolidine-2-carboxamide
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Structure
Formula
C29H39N5O2
Molecular Weight
489.664
Canonical SMILES
CCn1c2ccccc2n(C2CCN(CCCNC(=O)[C@H]3CCCN3Cc3ccccc3)CC2)c1=O
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InChI
InChI=1S/C29H39N5O2/c1-2-33-25-12-6-7-13-26(25)34(29(33)36)24-15-20-31(21-16-24)18-9-17-30-28(35)27-14-8-19-32(27)22-23-10-4-3-5-11-23/h3-7,10-13,24,27H,2,8-9,14-22H2,1H3,(H,30,35)/t27-/m1/s1
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InChIKey
SDNDZFFAQNCHOA-HHHXNRCGSA-N
Physicochemical Property
logP
3.6307
Rotatable Bonds
9
Heavy Atom Count
36
Polar Areas
62.51
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 54583469
ChEMBL ID
CHEMBL1783828
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS