General Information of the Compound
Compound ID
CP0532369
Compound Name
N-[(2R)-1-[(1,6-diamino-1-oxohexan-2-yl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]spiro[indene-1,4'-piperidine]-1'-carboxamide
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Structure
Formula
C31H38N6O3
Molecular Weight
542.684
Canonical SMILES
NCCCCC(NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)N1CCC2(CC1)C=Cc1ccccc21)C(N)=O
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InChI
InChI=1S/C31H38N6O3/c32-16-6-5-11-26(28(33)38)35-29(39)27(19-22-20-34-25-10-4-2-8-23(22)25)36-30(40)37-17-14-31(15-18-37)13-12-21-7-1-3-9-24(21)31/h1-4,7-10,12-13,20,26-27,34H,5-6,11,14-19,32H2,(H2,33,38)(H,35,39)(H,36,40)/t26?,27-/m1/s1
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InChIKey
KFEYKPBWXSDNLI-SSYAZFEXSA-N
Physicochemical Property
logP
2.9483
Rotatable Bonds
10
Heavy Atom Count
40
Polar Areas
146.34
Hydrogen Bond Donor Count
5
Hydrogen Bond Acceptor Count
4
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 10602592
SID: 15631917
ChEMBL ID
CHEMBL2112222
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01505, Somatostatin receptor type 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 53 nM
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