General Information of the Compound
Compound ID
CP0531587
Compound Name
CHEMBL4556227
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Formula
C26H39N3O
Molecular Weight
409.618
Canonical SMILES
CC(C)[C@H]1CC[C@H](CC1)N1CCC(CC1)n1cc(CN2CC(O)C2)c2ccccc12
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InChI
InChI=1S/C26H39N3O/c1-19(2)20-7-9-22(10-8-20)28-13-11-23(12-14-28)29-16-21(15-27-17-24(30)18-27)25-5-3-4-6-26(25)29/h3-6,16,19-20,22-24,30H,7-15,17-18H2,1-2H3/t20-,22+
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InChIKey
LCHNDEARQJNFQA-GRGXKFILSA-N
Physicochemical Property
logP
4.6695
Rotatable Bonds
5
Heavy Atom Count
30
Polar Areas
31.64
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4556227
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01200, Delta-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
Protein ID: PT00983, Kappa-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 1559 nM
   TI
   LI
   LO
   TS
2
Ki = 23.6 nM
   TI
   LI
   LO
   TS