General Information of the Compound
Compound ID
CP0528579
Compound Name
1-(2-(1-(4-methoxybenzyl)-5-(4-methoxyphenethyl)-4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazin-2-ylamino)ethyl)guanidine
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Structure
Formula
C23H29N7O4
Molecular Weight
467.53
Canonical SMILES
COc1ccc(CCn2c(=O)nc(NCCN=C(N)N)n(Cc3ccc(OC)cc3)c2=O)cc1
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InChI
InChI=1S/C23H29N7O4/c1-33-18-7-3-16(4-8-18)11-14-29-22(31)28-21(27-13-12-26-20(24)25)30(23(29)32)15-17-5-9-19(34-2)10-6-17/h3-10H,11-15H2,1-2H3,(H4,24,25,26)(H,27,28,31)
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InChIKey
IYCHVGAWBULNOX-UHFFFAOYSA-N
Physicochemical Property
logP
0.3985
Rotatable Bonds
11
Heavy Atom Count
34
Polar Areas
151.78
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
9
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11950138
SID: 17391497
ChEMBL ID
CHEMBL560171
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04583, Prokineticin receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 461 nM
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