General Information of the Compound
Compound ID
CP0528129
Compound Name
N-(3-aminophenyl)benzenesulfonamide
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Synonyms
104997-09-3
3-benzenesulfonylaminoaniline
3-phenylsulfonamidoaniline
A839866
AC1Q51QH
ACMC-20f7rf
ACN-049935
AKOS000132984
BDBM50193461
Benzenesulfonamide, N-(3-aminophenyl)-
CHEMBL378618
CTK0G5849
DTXSID40474387
EN300-40178
MCULE-1854488236
MolPort-004-296-827
N-(3-aminophenyl)benzenesulfonamide
NE22031
RUYQFOIEMVGGQT-UHFFFAOYSA-N
SCHEMBL2723618
ZINC22145186
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Structure
Formula
C12H12N2O2S
Molecular Weight
248.307
Canonical SMILES
Nc1cccc(NS(=O)(=O)c2ccccc2)c1
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InChI
InChI=1S/C12H12N2O2S/c13-10-5-4-6-11(9-10)14-17(15,16)12-7-2-1-3-8-12/h1-9,14H,13H2
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InChIKey
RUYQFOIEMVGGQT-UHFFFAOYSA-N
Physicochemical Property
logP
2.0696
Rotatable Bonds
3
Heavy Atom Count
17
Polar Areas
72.19
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
17

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11849198
SID: 17161984
ChEMBL ID
CHEMBL378618
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 2840 nM
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( N-(3-aminophenyl)benzenesulfonamide )
Drug Name N-(3-aminophenyl)benzenesulfonamide
Target(s)
5-HT 6 receptor (HTR6)
Inhibitor