General Information of the Compound
Compound ID
CP0528079
Compound Name
5-(4-methylpiperazin-1-yl)-2-nitro-N-(pyridin-3-ylmethyl)benzenamine
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Structure
Formula
C17H21N5O2
Molecular Weight
327.388
Canonical SMILES
CN1CCN(CC1)c1ccc(c(NCc2cccnc2)c1)[N+]([O-])=O
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InChI
InChI=1S/C17H21N5O2/c1-20-7-9-21(10-8-20)15-4-5-17(22(23)24)16(11-15)19-13-14-3-2-6-18-12-14/h2-6,11-12,19H,7-10,13H2,1H3
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InChIKey
UGIONADHPAWLPG-UHFFFAOYSA-N
Physicochemical Property
logP
2.3537
Rotatable Bonds
5
Heavy Atom Count
24
Polar Areas
74.54
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 2906372
SID: 16748953
ChEMBL ID
CHEMBL251201
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 1267 nM
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