General Information of the Compound
Compound ID
CP0526994
Compound Name
CHEMBL2046868
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Formula
C23H28N2
Molecular Weight
332.491
Canonical SMILES
C[C@H]1C[C@H]2[C@@H](C1)[C@@]2(N1CCN(CC1)c1ccccc1)c1ccccc1
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InChI
InChI=1S/C23H28N2/c1-18-16-21-22(17-18)23(21,19-8-4-2-5-9-19)25-14-12-24(13-15-25)20-10-6-3-7-11-20/h2-11,18,21-22H,12-17H2,1H3/t18-,21-,22+,23+
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InChIKey
GSIAQBZHBGRNHL-DMLMQYFOSA-N
Physicochemical Property
logP
4.38
Rotatable Bonds
3
Heavy Atom Count
25
Polar Areas
6.48
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL2046868
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02259, Neuropeptide Y receptor type 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  1
1
IC50 = 2200 nM
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