General Information of the Compound
Compound ID
CP0526992
Compound Name
1-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-3-(2H-tetrazol-5-ylmethyl)benzimidazol-2-one
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Structure
Formula
C28H37N7O3
Molecular Weight
519.65
Canonical SMILES
COc1ccc(C)c(OC(CCN2CCC(CC2)n2c3ccccc3n(Cc3nnn[nH]3)c2=O)C(C)C)c1
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InChI
InChI=1S/C28H37N7O3/c1-19(2)25(38-26-17-22(37-4)10-9-20(26)3)13-16-33-14-11-21(12-15-33)35-24-8-6-5-7-23(24)34(28(35)36)18-27-29-31-32-30-27/h5-10,17,19,21,25H,11-16,18H2,1-4H3,(H,29,30,31,32)
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InChIKey
UWNSOTJULHQSPQ-UHFFFAOYSA-N
Physicochemical Property
logP
3.81202
Rotatable Bonds
10
Heavy Atom Count
38
Polar Areas
103.09
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
9
Complexity
38

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44451620
ChEMBL ID
CHEMBL259262
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1023.29 nM
   TI
   LI
   LO
   TS
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 912.01 nM
   TI
   LI
   LO
   TS