General Information of the Compound
Compound ID
CP0526476
Compound Name
5-Chloro-N-(4-{[8-({[5-(dimethylamino)-1-naphthyl]sulfonyl}-amino)octyl]oxy}-3-piperazin-1-ylphenyl)-3-methyl-1-benzothiophene-2-sulfonamide
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Structure
Formula
C39H48ClN5O5S3
Molecular Weight
798.497
Canonical SMILES
CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCCCCOc1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)cc1N1CCNCC1
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InChI
InChI=1S/C39H48ClN5O5S3/c1-28-33-26-29(40)16-19-37(33)51-39(28)53(48,49)43-30-17-18-36(35(27-30)45-23-21-41-22-24-45)50-25-9-7-5-4-6-8-20-42-52(46,47)38-15-11-12-31-32(38)13-10-14-34(31)44(2)3/h10-19,26-27,41-43H,4-9,20-25H2,1-3H3
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InChIKey
AJFCFFCXDVYDDM-UHFFFAOYSA-N
Physicochemical Property
logP
7.99062
Rotatable Bonds
17
Heavy Atom Count
53
Polar Areas
120.08
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
9
Complexity
53

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 49781036
SID: 103055095
ChEMBL ID
CHEMBL1256255
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 741 nM
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