General Information of the Compound
Compound ID
CP0526242
Compound Name
2-(2-(3-(4-chlorobenzyl)-1,2,4-oxadiazol-5-yl)-1H-indol-4-yl)-N,N-dimethylethanamine
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Structure
Formula
C21H21ClN4O
Molecular Weight
380.879
Canonical SMILES
CN(C)CCc1cccc2[nH]c(cc12)-c1nc(Cc2ccc(Cl)cc2)no1
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InChI
InChI=1S/C21H21ClN4O/c1-26(2)11-10-15-4-3-5-18-17(15)13-19(23-18)21-24-20(25-27-21)12-14-6-8-16(22)9-7-14/h3-9,13,23H,10-12H2,1-2H3
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InChIKey
SJPXQFZWQMXEET-UHFFFAOYSA-N
Physicochemical Property
logP
4.5662
Rotatable Bonds
6
Heavy Atom Count
27
Polar Areas
57.95
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 136043817
ChEMBL ID
CHEMBL212161
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 450 nM
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