General Information of the Compound
Compound ID
CP0525452
Compound Name
(4S)-4-amino-5-[[(2S,3R)-1-[(2R)-2-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2R)-1-[[(1S)-1-carboxy-2-methylpropyl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid
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Structure
Formula
C53H77N11O17S2
Molecular Weight
1204.393
Canonical SMILES
CC(C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CS)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O)C(O)=O
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InChI
InChI=1S/C53H77N11O17S2/c1-27(2)42(53(80)81)62-50(77)38(26-83)61-47(74)35(23-30-14-16-31(66)17-15-30)57-45(72)33(12-7-8-20-54)56-46(73)34(22-29-10-5-4-6-11-29)58-49(76)37(25-82)60-48(75)36(24-41(69)70)59-51(78)39-13-9-21-64(39)52(79)43(28(3)65)63-44(71)32(55)18-19-40(67)68/h4-6,10-11,14-17,27-28,32-39,42-43,65-66,82-83H,7-9,12-13,18-26,54-55H2,1-3H3,(H,56,73)(H,57,72)(H,58,76)(H,59,78)(H,60,75)(H,61,74)(H,62,77)(H,63,71)(H,67,68)(H,69,70)(H,80,81)/t28-,32+,33+,34+,35+,36+,37+,38+,39-,42+,43+/m1/s1
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InChIKey
OSQTYEDYJVVPSO-XVZISOOWSA-N
Physicochemical Property
logP
-3.1764
Rotatable Bonds
35
Heavy Atom Count
83
Polar Areas
457.51
Hydrogen Bond Donor Count
17
Hydrogen Bond Acceptor Count
18
Complexity
83

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44296607
ChEMBL ID
CHEMBL386634
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02463, Urotensin-2 receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS