General Information of the Compound
Compound ID
CP0524543
Compound Name
2-[(1S)-5-{3-[4-(4-methoxypyridin-3-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid
    Show/Hide
Structure
Formula
C26H27NO5
Molecular Weight
433.504
Canonical SMILES
COc1ccncc1-c1ccc(OCCCOc2ccc3[C@H](CC(O)=O)CCc3c2)cc1
    Show/Hide
InChI
InChI=1S/C26H27NO5/c1-30-25-11-12-27-17-24(25)18-5-7-21(8-6-18)31-13-2-14-32-22-9-10-23-19(15-22)3-4-20(23)16-26(28)29/h5-12,15,17,20H,2-4,13-14,16H2,1H3,(H,28,29)/t20-/m0/s1
    Show/Hide
InChIKey
HVUXJWMRVBQKNL-FQEVSTJZSA-N
Physicochemical Property
logP
5.1096
Rotatable Bonds
10
Heavy Atom Count
32
Polar Areas
77.88
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 16110440
SID: 24757272
ChEMBL ID
CHEMBL220388
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02973, Peroxisome proliferator-activated receptor gamma
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000384 3T3-L1 Mus musculus (Mouse)  1
1
EC50 = 485 nM
   TI
   LI
   LO
   TS