General Information of the Compound
Compound ID
CP0520069
Compound Name
N-[[5-(3,5-dichlorophenyl)furan-2-yl]methyl]-2-(5-methoxy-1H-indol-3-yl)ethanamine
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Structure
Formula
C22H20Cl2N2O2
Molecular Weight
415.32
Canonical SMILES
COc1ccc2[nH]cc(CCNCc3ccc(o3)-c3cc(Cl)cc(Cl)c3)c2c1
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InChI
InChI=1S/C22H20Cl2N2O2/c1-27-18-2-4-21-20(11-18)14(12-26-21)6-7-25-13-19-3-5-22(28-19)15-8-16(23)10-17(24)9-15/h2-5,8-12,25-26H,6-7,13H2,1H3
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InChIKey
WICNFMTYERIDMA-UHFFFAOYSA-N
Physicochemical Property
logP
6.0756
Rotatable Bonds
7
Heavy Atom Count
28
Polar Areas
50.19
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 155557143
ChEMBL ID
CHEMBL4556193
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 210 nM
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