General Information of the Compound
Compound ID
CP0519879
Compound Name
2-[3-fluoro-4-(methanesulfonamido)phenyl]-N-[[2-hexoxy-4-methyl-6-(trifluoromethyl)pyridin-3-yl]methyl]propanamide
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Structure
Formula
C24H31F4N3O4S
Molecular Weight
533.588
Canonical SMILES
CCCCCCOc1nc(cc(C)c1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1)C(F)(F)F
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InChI
InChI=1S/C24H31F4N3O4S/c1-5-6-7-8-11-35-23-18(15(2)12-21(30-23)24(26,27)28)14-29-22(32)16(3)17-9-10-20(19(25)13-17)31-36(4,33)34/h9-10,12-13,16,31H,5-8,11,14H2,1-4H3,(H,29,32)
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InChIKey
XGRJYEAKSQJCCL-UHFFFAOYSA-N
Physicochemical Property
logP
5.29842
Rotatable Bonds
12
Heavy Atom Count
36
Polar Areas
97.39
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 67439048
ChEMBL ID
CHEMBL3407956
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02183, Transient receptor potential cation channel subfamily V member 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 100 nM
   TI
   LI
   LO
   TS