General Information of the Compound
Compound ID
CP0516787
Compound Name
US8901315, 331
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Structure
Formula
C20H27N5O3S
Molecular Weight
417.535
Canonical SMILES
CC[C@H](CN1C(=O)CNC1=O)NC(=O)c1cc2c(C)nn(C3CCCCC3)c2s1
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InChI
InChI=1S/C20H27N5O3S/c1-3-13(11-24-17(26)10-21-20(24)28)22-18(27)16-9-15-12(2)23-25(19(15)29-16)14-7-5-4-6-8-14/h9,13-14H,3-8,10-11H2,1-2H3,(H,21,28)(H,22,27)/t13-/m1/s1
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InChIKey
GSGOGRAJONDNBK-CYBMUJFWSA-N
Physicochemical Property
logP
2.97162
Rotatable Bonds
6
Heavy Atom Count
29
Polar Areas
96.33
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 57698165
ChEMBL ID
CHEMBL3650310
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01728, High affinity 3',5'-cyclic-AMP phosphodiesterase 7A
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000116 MOLT-4 Homo sapiens (Human)  1
1
IC50 = 29 nM
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