General Information of the Compound
| Compound ID |
CP0514791
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| Compound Name |
N-methyl-N-[[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-6-yl]methyl]-5-[2-methyl-4-(1,3,5-trimethylpyrazol-4-yl)phenyl]-1,3,4-oxadiazol-2-amine
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| Formula |
C28H29N9O
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| Molecular Weight |
507.602
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| Canonical SMILES |
CN(Cc1ccc2ncc(-c3cnn(C)c3)n2c1)c1nnc(o1)-c1ccc(cc1C)-c1c(C)nn(C)c1C
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| InChI |
InChI=1S/C28H29N9O/c1-17-11-21(26-18(2)33-36(6)19(26)3)8-9-23(17)27-31-32-28(38-27)34(4)14-20-7-10-25-29-13-24(37(25)15-20)22-12-30-35(5)16-22/h7-13,15-16H,14H2,1-6H3
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| InChIKey |
UYUHIXSXWHTNEO-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT01661, Tyrosine-protein kinase receptor TYRO3
Protein ID: PT01128, Tyrosine-protein kinase receptor UFO