General Information of the Compound
Compound ID
CP0512581
Compound Name
butyl N-[5-(2-methylpropyl)-3-[3-[2-(2-propan-2-ylimidazol-1-yl)acetyl]phenyl]thiophen-2-yl]sulfonylcarbamate
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Formula
C27H35N3O5S2
Molecular Weight
545.727
Canonical SMILES
CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1cccc(c1)C(=O)Cn1ccnc1C(C)C
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InChI
InChI=1S/C27H35N3O5S2/c1-6-7-13-35-27(32)29-37(33,34)26-23(16-22(36-26)14-18(2)3)20-9-8-10-21(15-20)24(31)17-30-12-11-28-25(30)19(4)5/h8-12,15-16,18-19H,6-7,13-14,17H2,1-5H3,(H,29,32)
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InChIKey
ATVNVSKNSMQOOJ-UHFFFAOYSA-N
Physicochemical Property
logP
6.0314
Rotatable Bonds
12
Heavy Atom Count
37
Polar Areas
107.36
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
8
Complexity
37

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4759641
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01553, Type-2 angiotensin II receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 17 nM
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