General Information of the Compound
Compound ID
CP0511844
Compound Name
8-benzhydryl-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol
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Structure
Formula
C26H27NO
Molecular Weight
369.508
Canonical SMILES
OC1(CC2CCC(C1)N2C(c1ccccc1)c1ccccc1)c1ccccc1
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InChI
InChI=1S/C26H27NO/c28-26(22-14-8-3-9-15-22)18-23-16-17-24(19-26)27(23)25(20-10-4-1-5-11-20)21-12-6-2-7-13-21/h1-15,23-25,28H,16-19H2
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InChIKey
CLYMVAVVSSYJKT-UHFFFAOYSA-N
Physicochemical Property
logP
5.2906
Rotatable Bonds
4
Heavy Atom Count
28
Polar Areas
23.47
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 10155966
SID: 15149081
ChEMBL ID
CHEMBL511920
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 94 nM
   TI
   LI
   LO
   TS
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 2.3 nM
   TI
   LI
   LO
   TS