General Information of the Compound
Compound ID
CP0509721
Compound Name
N-(3-methylbutyl)-10-(4-propan-2-ylphenyl)sulfonyl-5-thia-1,8,11,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),3,7,9,11-pentaen-7-amine
    Show/Hide
Structure
Formula
C21H25N5O2S2
Molecular Weight
443.598
Canonical SMILES
CC(C)CCNc1nc2c(nnn2c2ccsc12)S(=O)(=O)c1ccc(cc1)C(C)C
    Show/Hide
InChI
InChI=1S/C21H25N5O2S2/c1-13(2)9-11-22-19-18-17(10-12-29-18)26-20(23-19)21(24-25-26)30(27,28)16-7-5-15(6-8-16)14(3)4/h5-8,10,12-14H,9,11H2,1-4H3,(H,22,23)
    Show/Hide
InChIKey
CLLMJVSJTJGWKG-UHFFFAOYSA-N
Physicochemical Property
logP
4.7532
Rotatable Bonds
7
Heavy Atom Count
30
Polar Areas
89.25
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
8
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 20901177
ChEMBL ID
CHEMBL1172864
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 > 5000 nM
   TI
   LI
   LO
   TS