General Information of the Compound
Compound ID
CP0507917
Compound Name
N-ethyl-4-methoxy-N-naphthalen-1-yl-2-(2-propan-2-ylphenyl)-5,6,7,8-tetrahydroquinolin-5-amine
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Structure
Formula
C31H34N2O
Molecular Weight
450.626
Canonical SMILES
CCN(C1CCCc2nc(cc(OC)c12)-c1ccccc1C(C)C)c1cccc2ccccc12
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InChI
InChI=1S/C31H34N2O/c1-5-33(28-18-10-13-22-12-6-7-15-24(22)28)29-19-11-17-26-31(29)30(34-4)20-27(32-26)25-16-9-8-14-23(25)21(2)3/h6-10,12-16,18,20-21,29H,5,11,17,19H2,1-4H3
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InChIKey
DGSPLOHGPZJAPM-UHFFFAOYSA-N
Physicochemical Property
logP
7.9377
Rotatable Bonds
6
Heavy Atom Count
34
Polar Areas
25.36
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 25193028
SID: 57301719
ChEMBL ID
CHEMBL259642
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02772, C5a anaphylatoxin chemotactic receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937 Homo sapiens (Human)  1
1
IC50 = 1700 nM
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