General Information of the Compound
| Compound ID |
CP0507577
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| Compound Name |
N-[5-cyano-4-(2-methoxyethoxy)pyridin-2-yl]-7-formyl-6-[(2,2,4-trimethyl-6-oxopiperazin-1-yl)methyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
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| Formula |
C27H33N7O5
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| Molecular Weight |
535.605
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| Canonical SMILES |
COCCOc1cc(NC(=O)N2CCCc3cc(CN4C(=O)CN(C)CC4(C)C)c(C=O)nc23)ncc1C#N
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| InChI |
InChI=1S/C27H33N7O5/c1-27(2)17-32(3)15-24(36)34(27)14-19-10-18-6-5-7-33(25(18)30-21(19)16-35)26(37)31-23-11-22(39-9-8-38-4)20(12-28)13-29-23/h10-11,13,16H,5-9,14-15,17H2,1-4H3,(H,29,31,37)
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| InChIKey |
CTLARXIVBWEUOC-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01343, Fibroblast growth factor receptor 4
Protein ID: PT07029, Fibroblast growth factor receptor 4