General Information of the Compound
| Compound ID |
CP0507576
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| Compound Name |
N-[5-cyano-4-(2-methoxyethoxy)pyridin-2-yl]-7-formyl-6-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
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| Formula |
C26H29F3N6O4
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| Molecular Weight |
546.55
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| Canonical SMILES |
COCCOc1cc(NC(=O)N2CCCc3cc(C4CCN(CC(F)(F)F)CC4)c(C=O)nc23)ncc1C#N
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| InChI |
InChI=1S/C26H29F3N6O4/c1-38-9-10-39-22-12-23(31-14-19(22)13-30)33-25(37)35-6-2-3-18-11-20(21(15-36)32-24(18)35)17-4-7-34(8-5-17)16-26(27,28)29/h11-12,14-15,17H,2-10,16H2,1H3,(H,31,33,37)
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| InChIKey |
OLZQDHRXJOXCLL-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01343, Fibroblast growth factor receptor 4
Protein ID: PT07029, Fibroblast growth factor receptor 4