General Information of the Compound
Compound ID
CP0505271
Compound Name
5-(4-chloro-2-ethoxyphenyl)-4-methyl-N-(oxan-4-yl)-1,2-oxazole-3-carboxamide
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Structure
Formula
C18H21ClN2O4
Molecular Weight
364.829
Canonical SMILES
CCOc1cc(Cl)ccc1-c1onc(C(=O)NC2CCOCC2)c1C
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InChI
InChI=1S/C18H21ClN2O4/c1-3-24-15-10-12(19)4-5-14(15)17-11(2)16(21-25-17)18(22)20-13-6-8-23-9-7-13/h4-5,10,13H,3,6-9H2,1-2H3,(H,20,22)
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InChIKey
NKHTVYWORXECGR-UHFFFAOYSA-N
Physicochemical Property
logP
3.61092
Rotatable Bonds
5
Heavy Atom Count
25
Polar Areas
73.59
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 56670093
ChEMBL ID
CHEMBL1807881
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02183, Transient receptor potential cation channel subfamily V member 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 12.59 nM
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