General Information of the Compound
Compound ID
CP0503847
Compound Name
US8772323, 97
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Structure
Formula
C18H17N3O2S
Molecular Weight
339.42
Canonical SMILES
CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1cc(C)cs1
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InChI
InChI=1S/C18H17N3O2S/c1-3-11-8-16(22)20-21-17(11)12-4-5-13-14(7-12)23-18(19-13)15-6-10(2)9-24-15/h4-7,9,11H,3,8H2,1-2H3,(H,20,22)
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InChIKey
XBOVDQOTNPNLDE-UHFFFAOYSA-N
Physicochemical Property
logP
4.11492
Rotatable Bonds
3
Heavy Atom Count
24
Polar Areas
67.49
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 67466124
ChEMBL ID
CHEMBL3944973
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02455, Glucose-dependent insulinotropic receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000613 MIN6 Mus musculus (Mouse)  1
1
EC50 = 225 nM
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