General Information of the Compound
Compound ID
CP0502316
Compound Name
(2R)-1-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)-3-(2-methyl-1-phenylpropoxy)propan-2-ol
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Structure
Formula
C27H35NO2
Molecular Weight
405.582
Canonical SMILES
CC(C)C(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1
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InChI
InChI=1S/C27H35NO2/c1-20(2)26(23-11-6-5-7-12-23)30-19-25(29)18-28-27(3,4)17-21-14-15-22-10-8-9-13-24(22)16-21/h5-16,20,25-26,28-29H,17-19H2,1-4H3/t25-,26?/m1/s1
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InChIKey
IICXUBMRVLNRHY-DCWQJPKNSA-N
Physicochemical Property
logP
5.5253
Rotatable Bonds
10
Heavy Atom Count
30
Polar Areas
41.49
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46891416
ChEMBL ID
CHEMBL1082717
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01916, Extracellular calcium-sensing receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000868 PC12 Rattus norvegicus (Rat)  1
1
IC50 = 200 nM
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