General Information of the Compound
Compound ID
CP0502161
Compound Name
N-[8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-yl]cyclopropanecarboxamide
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Structure
Formula
C30H30Cl2N2O
Molecular Weight
505.489
Canonical SMILES
Clc1ccccc1C(N1C2CCC1CC(C2)(NC(=O)C1CC1)c1ccccc1)c1ccccc1Cl
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InChI
InChI=1S/C30H30Cl2N2O/c31-26-12-6-4-10-24(26)28(25-11-5-7-13-27(25)32)34-22-16-17-23(34)19-30(18-22,21-8-2-1-3-9-21)33-29(35)20-14-15-20/h1-13,20,22-23,28H,14-19H2,(H,33,35)
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InChIKey
IQKRJMYITRFRAP-UHFFFAOYSA-N
Physicochemical Property
logP
7.1313
Rotatable Bonds
6
Heavy Atom Count
35
Polar Areas
32.34
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44574789
ChEMBL ID
CHEMBL466919
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 996 nM
   TI
   LI
   LO
   TS
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 11 nM
   TI
   LI
   LO
   TS