General Information of the Compound
Compound ID
CP0502027
Compound Name
(R)-1-[4-(2,2-Diphenylacetamido)-5-(4-hydroxybenzylamino)-5-oxopentyl]-2-{4-[4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl]butanoyl}guanidinium 2,2,2-trifluoroacetate
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Structure
Formula
C34H40N8O5
Molecular Weight
640.745
Canonical SMILES
NC(NC(=O)CCCn1cc(CO)nn1)=NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1
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InChI
InChI=1S/C34H40N8O5/c35-34(39-30(45)14-8-20-42-22-27(23-43)40-41-42)36-19-7-13-29(32(46)37-21-24-15-17-28(44)18-16-24)38-33(47)31(25-9-3-1-4-10-25)26-11-5-2-6-12-26/h1-6,9-12,15-18,22,29,31,43-44H,7-8,13-14,19-21,23H2,(H,37,46)(H,38,47)(H3,35,36,39,45)/t29-/m1/s1
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InChIKey
PKOSBEQUIDPYHS-GDLZYMKVSA-N
Physicochemical Property
logP
2.1006
Rotatable Bonds
16
Heavy Atom Count
47
Polar Areas
196.85
Hydrogen Bond Donor Count
6
Hydrogen Bond Acceptor Count
9
Complexity
47

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 49865808
ChEMBL ID
CHEMBL1223996
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02259, Neuropeptide Y receptor type 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  1
1
Ki = 3 nM
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