General Information of the Compound
Compound ID
CP0501988
Compound Name
1-[3-(3-cyanophenyl)cyclopent-2-en-1-yl]-3-(3,5-dichlorophenyl)-1-(2-pyrrolidin-1-ylethyl)urea
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Structure
Formula
C25H26Cl2N4O
Molecular Weight
469.416
Canonical SMILES
Clc1cc(Cl)cc(NC(=O)N(CCN2CCCC2)C2CCC(=C2)c2cccc(c2)C#N)c1
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InChI
InChI=1S/C25H26Cl2N4O/c26-21-14-22(27)16-23(15-21)29-25(32)31(11-10-30-8-1-2-9-30)24-7-6-20(13-24)19-5-3-4-18(12-19)17-28/h3-5,12-16,24H,1-2,6-11H2,(H,29,32)
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InChIKey
VTYHUUVATIQVFT-UHFFFAOYSA-N
Physicochemical Property
logP
6.04078
Rotatable Bonds
6
Heavy Atom Count
32
Polar Areas
59.37
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11641333
SID: 16744598
ChEMBL ID
CHEMBL437130
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01027, Melanin-concentrating hormone receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 605 nM
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