General Information of the Compound
Compound ID
CP0500680
Compound Name
N-[2-(4-chlorophenyl)ethyl]-4-[2-(dimethylamino)ethyl]-1H-indole-2-carboxamide
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Structure
Formula
C21H24ClN3O
Molecular Weight
369.896
Canonical SMILES
CN(C)CCc1cccc2[nH]c(cc12)C(=O)NCCc1ccc(Cl)cc1
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InChI
InChI=1S/C21H24ClN3O/c1-25(2)13-11-16-4-3-5-19-18(16)14-20(24-19)21(26)23-12-10-15-6-8-17(22)9-7-15/h3-9,14,24H,10-13H2,1-2H3,(H,23,26)
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InChIKey
XICBCXSYEQBJLS-UHFFFAOYSA-N
Physicochemical Property
logP
3.8979
Rotatable Bonds
7
Heavy Atom Count
26
Polar Areas
48.13
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44413183
ChEMBL ID
CHEMBL210043
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 > 1000 nM
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   LI
   LO
   TS