General Information of the Compound
Compound ID
CP0500573
Compound Name
2-(2-(3-((4-chlorophenoxy)methyl)-1,2,4-oxadiazol-5-yl)-1H-indol-4-yl)-N,N-dimethylethanamine
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Structure
Formula
C21H21ClN4O2
Molecular Weight
396.878
Canonical SMILES
CN(C)CCc1cccc2[nH]c(cc12)-c1nc(COc2ccc(Cl)cc2)no1
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InChI
InChI=1S/C21H21ClN4O2/c1-26(2)11-10-14-4-3-5-18-17(14)12-19(23-18)21-24-20(25-28-21)13-27-16-8-6-15(22)7-9-16/h3-9,12,23H,10-11,13H2,1-2H3
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InChIKey
COOPGBFJGAPBGH-UHFFFAOYSA-N
Physicochemical Property
logP
4.5544
Rotatable Bonds
7
Heavy Atom Count
28
Polar Areas
67.18
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 136043824
ChEMBL ID
CHEMBL212520
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 410 nM
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