General Information of the Compound
Compound ID
CP0500148
Compound Name
US8952150, 4
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Structure
Formula
C28H31N7O4
Molecular Weight
529.601
Canonical SMILES
Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccccc3)n2)cc1
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InChI
InChI=1S/C28H31N7O4/c36-24-13-11-23(12-14-24)32-28-34-26(33-27(35-28)31-22-9-5-2-6-10-22)30-16-18-39-20-19-38-17-15-29-25(37)21-7-3-1-4-8-21/h1-14,36H,15-20H2,(H,29,37)(H3,30,31,32,33,34,35)
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InChIKey
WFHONTNXDFUYJZ-UHFFFAOYSA-N
Physicochemical Property
logP
3.9395
Rotatable Bonds
15
Heavy Atom Count
39
Polar Areas
142.55
Hydrogen Bond Donor Count
5
Hydrogen Bond Acceptor Count
10
Complexity
39

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 51036345
SID: 117696845
ChEMBL ID
CHEMBL3650459
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06205, Solute carrier organic anion transporter family member 2A1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000031 MDCK Canis lupus familiaris (Dog)  1
1
IC50 = 4850 nM
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