General Information of the Compound
Compound ID
CP0500037
Compound Name
5-Chloro-N-(3-{4-[6-({[5-(dimethylamino)-1-naphthyl]sulfonyl}-amino)hexyl]piperazin-1-yl}-4-methoxyphenyl)-3-methyl-1-benzothiophene-2-sulfonamide
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Structure
Formula
C38H46ClN5O5S3
Molecular Weight
784.47
Canonical SMILES
COc1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)cc1N1CCN(CCCCCCNS(=O)(=O)c2cccc3c(cccc23)N(C)C)CC1
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InChI
InChI=1S/C38H46ClN5O5S3/c1-27-32-25-28(39)15-18-36(32)50-38(27)52(47,48)41-29-16-17-35(49-4)34(26-29)44-23-21-43(22-24-44)20-8-6-5-7-19-40-51(45,46)37-14-10-11-30-31(37)12-9-13-33(30)42(2)3/h9-18,25-26,40-41H,5-8,19-24H2,1-4H3
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InChIKey
WLPVWRBWBJKZPV-UHFFFAOYSA-N
Physicochemical Property
logP
7.55262
Rotatable Bonds
15
Heavy Atom Count
52
Polar Areas
111.29
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
9
Complexity
52

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 49782362
SID: 103054874
ChEMBL ID
CHEMBL1256250
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 266 nM
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   LI
   LO
   TS