General Information of the Compound
Compound ID
CP0499460
Compound Name
N,N-dimethyl-9-(4-methylphenyl)sulfonyl-6-methylsulfanyl-1,2,3,4-tetrahydrocarbazol-3-amine
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Structure
Formula
C22H26N2O2S2
Molecular Weight
414.596
Canonical SMILES
CSc1ccc2n(c3CCC(Cc3c2c1)N(C)C)S(=O)(=O)c1ccc(C)cc1
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InChI
InChI=1S/C22H26N2O2S2/c1-15-5-9-18(10-6-15)28(25,26)24-21-11-7-16(23(2)3)13-19(21)20-14-17(27-4)8-12-22(20)24/h5-6,8-10,12,14,16H,7,11,13H2,1-4H3
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InChIKey
LYGXTKJBXJMAQL-UHFFFAOYSA-N
Physicochemical Property
logP
4.32752
Rotatable Bonds
4
Heavy Atom Count
28
Polar Areas
42.31
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 16222871
SID: 24905362
ChEMBL ID
CHEMBL2165556
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 13.8 nM
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