General Information of the Compound
Compound ID
CP0498100
Compound Name
(2S)-N-[(1R)-2-hydroxy-2-methyl-1-[4-(2-methylpentoxy)phenyl]propyl]-2-phenylpropanamide
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Structure
Formula
C25H35NO3
Molecular Weight
397.559
Canonical SMILES
CCCC(C)COc1ccc(cc1)[C@@H](NC(=O)[C@@H](C)c1ccccc1)C(C)(C)O
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InChI
InChI=1S/C25H35NO3/c1-6-10-18(2)17-29-22-15-13-21(14-16-22)23(25(4,5)28)26-24(27)19(3)20-11-8-7-9-12-20/h7-9,11-16,18-19,23,28H,6,10,17H2,1-5H3,(H,26,27)/t18?,19-,23+/m0/s1
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InChIKey
DTNWRNSQLZVGLW-HXCXSPQYSA-N
Physicochemical Property
logP
5.2335
Rotatable Bonds
10
Heavy Atom Count
29
Polar Areas
58.56
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 51354469
SID: 121273400
ChEMBL ID
CHEMBL3403779
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03540, G protein-coupled receptor 88
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 270 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 39 nM