General Information of the Compound
Compound ID
CP0498088
Compound Name
methyl (2R)-2-[(1S,2R,3S,6S,8S,10S)-10-tert-butyl-2-hydroxy-16-methoxy-3-methyl-4,14-dioxo-5,13,15-trioxapentacyclo[7.5.2.01,8.02,6.08,12]hexadecan-9-yl]-2-methoxyacetate
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Structure
Formula
C23H32O10
Molecular Weight
468.499
Canonical SMILES
CO[C@@H](C(=O)OC)C12C(OC)O[C@@]34C(=O)OC(C[C@H]1C(C)(C)C)[C@]23C[C@@H]1OC(=O)[C@@H](C)[C@]41O
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InChI
InChI=1S/C23H32O10/c1-10-15(24)31-13-9-20-12-8-11(19(2,3)4)21(20,14(28-5)16(25)29-6)18(30-7)33-23(20,17(26)32-12)22(10,13)27/h10-14,18,27H,8-9H2,1-7H3/t10-,11+,12?,13+,14+,18?,20-,21?,22-,23+/m1/s1
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InChIKey
UNZQPJVKRCVMPC-KJCNSVPDSA-N
Physicochemical Property
logP
0.5764
Rotatable Bonds
4
Heavy Atom Count
33
Polar Areas
126.82
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
10
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44420851
ChEMBL ID
CHEMBL223081
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT05068, Glycine receptor subunit alpha-1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
Protein ID: PT06069, Glycine receptor subunit alpha-2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS