General Information of the Compound
Compound ID
CP0496826
Compound Name
2-benzyl-N-(3-{2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl}propyl)benzamide
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Structure
Formula
C30H34N2O
Molecular Weight
438.615
Canonical SMILES
O=C(NCCCN1CCC2(CCc3ccccc23)CC1)c1ccccc1Cc1ccccc1
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InChI
InChI=1S/C30H34N2O/c33-29(27-13-6-4-12-26(27)23-24-9-2-1-3-10-24)31-19-8-20-32-21-17-30(18-22-32)16-15-25-11-5-7-14-28(25)30/h1-7,9-14H,8,15-23H2,(H,31,33)
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InChIKey
XFIZETUANYXJSD-UHFFFAOYSA-N
Physicochemical Property
logP
5.3773
Rotatable Bonds
7
Heavy Atom Count
33
Polar Areas
32.34
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44407116
ChEMBL ID
CHEMBL202322
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 21 nM
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