General Information of the Compound
Compound ID
CP0496043
Compound Name
4-(3-(2,5-dimethylphenylsulfonyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-yl)morpholine
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Structure
Formula
C19H19N5O3S2
Molecular Weight
429.527
Canonical SMILES
Cc1ccc(C)c(c1)S(=O)(=O)c1nnn2c3ccsc3c(nc12)N1CCOCC1
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InChI
InChI=1S/C19H19N5O3S2/c1-12-3-4-13(2)15(11-12)29(25,26)19-18-20-17(23-6-8-27-9-7-23)16-14(5-10-28-16)24(18)22-21-19/h3-5,10-11H,6-9H2,1-2H3
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InChIKey
UUFXAVYQCCJGAI-UHFFFAOYSA-N
Physicochemical Property
logP
2.62524
Rotatable Bonds
3
Heavy Atom Count
29
Polar Areas
89.69
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
9
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 16019490
ChEMBL ID
CHEMBL1173709
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 1930 nM
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