General Information of the Compound
| Compound ID |
CP0494150
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| Compound Name |
N-methyl-N-[[3-(1-methylpiperidin-4-yl)imidazo[1,2-a]pyridin-6-yl]methyl]-5-[2-methyl-4-(1,3,5-trimethylpyrazol-4-yl)phenyl]-1,3,4-oxadiazol-2-amine
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| Formula |
C30H36N8O
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| Molecular Weight |
524.673
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| Canonical SMILES |
CN(Cc1ccc2ncc(C3CCN(C)CC3)n2c1)c1nnc(o1)-c1ccc(cc1C)-c1c(C)nn(C)c1C
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| InChI |
InChI=1S/C30H36N8O/c1-19-15-24(28-20(2)34-37(6)21(28)3)8-9-25(19)29-32-33-30(39-29)36(5)17-22-7-10-27-31-16-26(38(27)18-22)23-11-13-35(4)14-12-23/h7-10,15-16,18,23H,11-14,17H2,1-6H3
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| InChIKey |
IIMADOKMWMOETN-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT01661, Tyrosine-protein kinase receptor TYRO3
Protein ID: PT01128, Tyrosine-protein kinase receptor UFO