General Information of the Compound
Compound ID
CP0493778
Compound Name
N-[3-[1-[3-[3-(4-chlorophenyl)-6-oxopyridazin-1-yl]propyl]piperidin-4-yl]phenyl]acetamide
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Structure
Formula
C26H29ClN4O2
Molecular Weight
464.997
Canonical SMILES
CC(=O)Nc1cccc(c1)C1CCN(CCCn2nc(ccc2=O)-c2ccc(Cl)cc2)CC1
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InChI
InChI=1S/C26H29ClN4O2/c1-19(32)28-24-5-2-4-22(18-24)20-12-16-30(17-13-20)14-3-15-31-26(33)11-10-25(29-31)21-6-8-23(27)9-7-21/h2,4-11,18,20H,3,12-17H2,1H3,(H,28,32)
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InChIKey
NNCGMLUTAMGCGM-UHFFFAOYSA-N
Physicochemical Property
logP
4.7918
Rotatable Bonds
7
Heavy Atom Count
33
Polar Areas
67.23
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 57397816
ChEMBL ID
CHEMBL1934811
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01027, Melanin-concentrating hormone receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 120 nM
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