General Information of the Compound
Compound ID
CP0493503
Compound Name
(4bS,6aS,6bS,11aS,12aS,12bR)-2-Hydroxy-6a-methyl-4b,5,6,6a,6b,9,10,11,11a,12,12a,12b,13,14-tetradecahydro-7-oxa-azuleno[2,1-a]phenanthren-8-one
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Structure
Formula
C22H28O3
Molecular Weight
340.463
Canonical SMILES
C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1C[C@@H]1CCCC(=O)O[C@H]21
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InChI
InChI=1S/C22H28O3/c1-22-10-9-17-16-8-6-15(23)11-13(16)5-7-18(17)19(22)12-14-3-2-4-20(24)25-21(14)22/h6,8,11,14,17-19,21,23H,2-5,7,9-10,12H2,1H3/t14-,17+,18+,19-,21-,22-/m0/s1
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InChIKey
CUBJBNIDFCEHJC-IZSGYEDXSA-N
Physicochemical Property
logP
4.5701
Rotatable Bonds
0
Heavy Atom Count
25
Polar Areas
46.53
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11393656
SID: 16488403
ChEMBL ID
CHEMBL477880
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02692, Aldo-keto reductase family 1 member C3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 66 nM
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