General Information of the Compound
Compound ID
CP0493174
Compound Name
2-{2-[4-(6-Chloro-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-piperidin-1-yl]-acetylamino}-benzoic acid methyl ester
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Structure
Formula
C23H24ClN3O5
Molecular Weight
457.914
Canonical SMILES
COC(=O)c1ccccc1NC(=O)CN1CCC(CC1)N1C(=O)OCc2cc(Cl)ccc12
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InChI
InChI=1S/C23H24ClN3O5/c1-31-22(29)18-4-2-3-5-19(18)25-21(28)13-26-10-8-17(9-11-26)27-20-7-6-16(24)12-15(20)14-32-23(27)30/h2-7,12,17H,8-11,13-14H2,1H3,(H,25,28)
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InChIKey
BVYJNIUMOSPQEW-UHFFFAOYSA-N
Physicochemical Property
logP
3.6863
Rotatable Bonds
5
Heavy Atom Count
32
Polar Areas
88.18
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 9981549
SID: 14959550
ChEMBL ID
CHEMBL372724
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01653, Neuropeptide Y receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000049 C6 Rattus norvegicus (Rat)  1
1
IC50 > 1000 nM
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