General Information of the Compound
Compound ID
CP0492829
Compound Name
2,8-Dimethyl-5-((E)-styryl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
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Structure
Formula
C21H24N2
Molecular Weight
304.437
Canonical SMILES
CN1CCC2C(C1)c1cc(C)ccc1N2\C=C\c1ccccc1
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InChI
InChI=1S/C21H24N2/c1-16-8-9-20-18(14-16)19-15-22(2)12-11-21(19)23(20)13-10-17-6-4-3-5-7-17/h3-10,13-14,19,21H,11-12,15H2,1-2H3/b13-10+
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InChIKey
LBGASCXEDHLYEH-JLHYYAGUSA-N
Physicochemical Property
logP
4.27362
Rotatable Bonds
2
Heavy Atom Count
23
Polar Areas
6.48
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Complexity
23

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46224880
ChEMBL ID
CHEMBL601304
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 1680 nM
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