General Information of the Compound
| Compound ID |
CP0492710
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| Compound Name |
N-[(R)-1,3-thiazol-2-yl-[3-(trifluoromethyl)pyridin-2-yl]methyl]quinoline-7-carboxamide
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| Structure |
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| Formula |
C20H13F3N4OS
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| Molecular Weight |
414.412
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| Canonical SMILES |
FC(F)(F)c1cccnc1[C@@H](NC(=O)c1ccc2cccnc2c1)c1nccs1
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| InChI |
InChI=1S/C20H13F3N4OS/c21-20(22,23)14-4-2-8-25-16(14)17(19-26-9-10-29-19)27-18(28)13-6-5-12-3-1-7-24-15(12)11-13/h1-11,17H,(H,27,28)/t17-/m1/s1
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| InChIKey |
DPYLWNVKQKCNMS-QGZVFWFLSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03065, Transient receptor potential cation channel subfamily M member 8
Protein ID: PT06117, Transient receptor potential cation channel subfamily M member 8