General Information of the Compound
Compound ID
CP0491912
Compound Name
2-naphthalen-1-yl-N-(3-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylpropyl)acetamide
    Show/Hide
Structure
Formula
C28H32N2O
Molecular Weight
412.577
Canonical SMILES
O=C(Cc1cccc2ccccc12)NCCCN1CCC2(CCc3ccccc23)CC1
    Show/Hide
InChI
InChI=1S/C28H32N2O/c31-27(21-24-10-5-9-22-7-1-3-11-25(22)24)29-17-6-18-30-19-15-28(16-20-30)14-13-23-8-2-4-12-26(23)28/h1-5,7-12H,6,13-21H2,(H,29,31)
    Show/Hide
InChIKey
KCTKCFSYQPMZKE-UHFFFAOYSA-N
Physicochemical Property
logP
4.8686
Rotatable Bonds
6
Heavy Atom Count
31
Polar Areas
32.34
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 44406991
ChEMBL ID
CHEMBL372726
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS