General Information of the Compound
Compound ID
CP0491313
Compound Name
N-[4-(1-imidazol-1-ylethyl)phenyl]naphthalen-2-amine
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Structure
Formula
C21H19N3
Molecular Weight
313.404
Canonical SMILES
CC(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1
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InChI
InChI=1S/C21H19N3/c1-16(24-13-12-22-15-24)17-6-9-20(10-7-17)23-21-11-8-18-4-2-3-5-19(18)14-21/h2-16,23H,1H3
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InChIKey
FEJYVWPFDRSJOL-UHFFFAOYSA-N
Physicochemical Property
logP
5.3892
Rotatable Bonds
4
Heavy Atom Count
24
Polar Areas
29.85
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44569194
ChEMBL ID
CHEMBL460130
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02999, Cytochrome P450 26A1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7 Homo sapiens (Human)  1
1
IC50 = 15000 nM
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