General Information of the Compound
| Compound ID |
CP0489396
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| Compound Name |
(E)-N-hydroxy-3-[2-(2,3,4-trimethoxyphenyl)-1,3-thiazol-5-yl]prop-2-enamide
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| Structure |
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| Formula |
C15H16N2O5S
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| Molecular Weight |
336.369
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| Canonical SMILES |
COc1ccc(-c2ncc(\C=C\C(=O)NO)s2)c(OC)c1OC
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| InChI |
InChI=1S/C15H16N2O5S/c1-20-11-6-5-10(13(21-2)14(11)22-3)15-16-8-9(23-15)4-7-12(18)17-19/h4-8,19H,1-3H3,(H,17,18)/b7-4+
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| InChIKey |
WLURIJZBBHRHBR-QPJJXVBHSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01213, Histone deacetylase 6
Protein ID: PT01499, Histone deacetylase 8