General Information of the Compound
| Compound ID |
CP0487675
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
N'-hydroxy-N-[6-[3-(trifluoromethyl)phenyl]-1H-indazol-3-yl]octanediamide
Show/Hide
|
||||||||||||||||||
| Formula |
C22H23F3N4O3
|
||||||||||||||||||
| Molecular Weight |
448.445
|
||||||||||||||||||
| Canonical SMILES |
ONC(=O)CCCCCCC(=O)Nc1n[nH]c2cc(ccc12)-c1cccc(c1)C(F)(F)F
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C22H23F3N4O3/c23-22(24,25)16-7-5-6-14(12-16)15-10-11-17-18(13-15)27-28-21(17)26-19(30)8-3-1-2-4-9-20(31)29-32/h5-7,10-13,32H,1-4,8-9H2,(H,29,31)(H2,26,27,28,30)
Show/Hide
|
||||||||||||||||||
| InChIKey |
SAVUDVYKBKFKRL-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00991, Histone deacetylase 1
Protein ID: PT00835, Histone deacetylase 2
Protein ID: PT01499, Histone deacetylase 8